The algorithm ends here for these patients.Īfter 2 to 3 months, if TSH is equal to or less than 10 mIU/L AND TPO is negative If patient is symptomatic, offer a 3 to 6-month trial of levothyroxine treatment without any antibody testingĪfter 2 to 3 months, if TSH, T4 normal, TPO negative Measure TSH, T4, TPO antibodies in 2 to 3 months.
Subclinical thyroid disorder identified by testing requires careful clinical assessment of relevant symptoms, thyroid morphology and important comorbidities. If T4 is normal, this is subclinical hypothyroidism Further investigation lead to two further options based on T4 levels.